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              Review
                            
                            
                            13.  
                            
                            Ovarian stem cells and neo-oogenesis: A breakthrough 
                            in reproductive biology research - 
                            S. Mooyottu, S. Anees, S. Cherian
                            Vet World. 2011; 4(2): 89-91
              
              
               
              
              
              doi: 
              10.5455/vetworld.2011.89-91
              
              
               
              
              
              
   
 
              
               
               
               
              
              
              Abstract
              
                            
                            
                            The concept of ovarian stem cells which can 
                            replenish the ovarian reserve in postnatal mammalian 
                            females is a revolutionary breakthrough in 
                            reproductive biology. This idea overturned the 
                            central dogma existed in female reproductive 
                            physiology. Contradicting the popular belief that 
                            oogenesis does not occur in post natal life, 
                            researchers proved the existence of putative stem 
                            cells in ovary, which can supply functional 
                            follicles in post natal ovaries. Even though the 
                            idea of neo-oogenesis in postnatal ovaries in normal 
                            conditions is controversial, the isolation and 
                            manipulation of ovarian stem cells have got 
                            tremendous application in medical, veterinary and 
                            animal production fields. 
              
                            
              Key words: Germline 
                            stem cells (GSC), Ovarian stem cells, Neo-oogenesis